Myasthenia gravis is an autoimmune disorder of neuromuscular transmission, characterized by
fluctuating muscle weakness and fatigability. In isolated ocular myasthenia, when only the
extraocular muscles are involved, most common ancillary tests, such as acetylcholine receptor
autoantibodies and repetitive nerve stimulation, are often negative.
A simple, quick and non-invasive test for ocular myasthenia based on ocular vestibular evoked
myogenic potentials (oVEMP) was recently developed.
The main goal of the study is to validate repetitive oVEMP stimulation in a blinded
diagnostic accuracy study in order to facilitate early and accurate diagnosis of ocular