This trial is completed!
Search for a recruiting clinical trial for your condition
Your journey
1What's a trial
2Find
3Review
4Get in touch
More info
You can access this
clinical trial
if you have
Cystic Fibrosis
and you are
over 18
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
Show me locations

The purpose

Evaluate the safety and tolerability of VX-659 in healthy subjects

Provided treatments

  • Drug: VX-659
  • Drug: Tezacaftor
  • Drug: Ivacaftor
  • Drug: VX-659 Matching Placebo
  • Drug: Triple Combination (TC) Matching Placebos
Tris trial is registered with FDA with number: NCT03029455. The sponsor of the trial is Vertex Pharmaceuticals Incorporated and it is looking for 163 volunteers for the current phase.
Official trial title:
A Phase 1, Randomized, Double Blind, Placebo Controlled, Dose Escalation, and Bioavailability Study Evaluating the Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Subjects With Cystic Fibrosis