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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Cystic Fibrosis
and you are
over 18
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

Evaluate the safety and tolerability of VX-659 in healthy subjects

Provided treatments

  • Drug: VX-659
  • Drug: Tezacaftor
  • Drug: Ivacaftor
  • Drug: VX-659 Matching Placebo
  • Drug: Triple Combination (TC) Matching Placebos

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03029455. The sponsor of the trial is Vertex Pharmaceuticals Incorporated and it is looking for 163 volunteers for the current phase.
Official trial title:
A Phase 1, Randomized, Double Blind, Placebo Controlled, Dose Escalation, and Bioavailability Study Evaluating the Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Subjects With Cystic Fibrosis