Arrhythmias accompany septic shock in increased rates than in other ICU cohorts and their
presence and management are related to patient´s prognosis. 1c class antiarrhythmics are
seldom administered in intensive care due to a dose dependent toxicity published in case
reports and unfavourable outcome reported in a few prospective trials done on cardiology
patients. The papers on 1c class antiarrhythmics do not take into consideration a complex
haemodynamic assessment using echocardiography. The authors have recently presented a
retrospective study on SV arrhythmias in septic shock patients demonstrating favourable
effect and safety of propafenone which showed higher antiarrhythmic efficacy than amiodarone.