This study will assess changes in visual acuity and corneal symmetry after corneal collagen
cross-linking (CXL) of asymmetric corneas.
Compound Product: CXLO Corneal Strengthening Solution and UVA Illumination Device
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Locations near you
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Full eligibility criteria for NCT03029104
Ages eligible for Study
8 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
A diagnosis of at least one of the following conditions:
Forme fruste keratoconus
Pellucid marginal degeneration
Forme fruste pellucid marginal degeneration
Diurnal fluctuation post-radial keratotomy
Terrien's marginal degeneration
Corneal thickness < 375 microns measured by ultrasound or Pentacam.
Contraindications or hypersensitivities to any study medications or their components.
Pregnancy or breastfeeding.
Any history of herpes simplex corneal disease in an eye to be treated.
Nystagmus or any other condition that would, in the judgement of the investigator, prevent a steady gaze during the treatment.
Inability to cooperate with diagnostic tests.
Enrollment in another ophthalmic clinical trial.
All locations for NCT03029104
United States (9)
Schwartz Laser Eye Center
Scottsdale, Arizona, United States, 85260
Goodman Eye Center
San Francisco, California, United States, 94115
Cornea Consultants of Colorado
Littleton, Colorado, United States, 80120-4508
Woolfson Eye Institute
Atlanta, Georgia, United States, 30328
Chicago Cornea Consultants
Chicago, Illinois, United States, 60035
Chicago Cornea Consultants, Ltd.
Hoffman Estates, Illinois, United States, 60169
Saint Louis, Missouri, United States, 63110
Cleveland Eye Clinic
Brecksville, Ohio, United States, 44141
Cornea Associates of Texas
Dallas, Texas, United States, 75231
View full eligibility
Tris trial is registered with FDA with number: NCT03029104. The sponsor of the trial is Cxlusa and it is looking for 3000 volunteers for the current phase.
Official trial title: COLLAGEN CROSS-LINKING WITH ULTRAVIOLET-A IN ASYMMETRIC CORNEAS
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