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You can access this
clinical trial
if you have
Hypopharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma or Larynx Cancer
and you are
between 18 and 70
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This trial is to determine what dose of a drug called AZD1775 can safely be given in combination with cisplatin before surgery and with chemo-radiotherapy after surgery in patients with Head and Neck Cancer. The Investigators will also get some preliminary information regarding the effectiveness of this combined treatment.

Provided treatments

  • Drug: AZD1775
  • Drug: Cisplatin
  • Radiation: Radiotherapy
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Locations near you

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Tris trial is registered with FDA with number: NCT03028766. The sponsor of the trial is University of Birmingham and it is looking for 42 volunteers for the current phase.
Official trial title:
A Phase I Trial of WEE1 Inhibition With Chemotherapy and Radiotherapy as Adjuvant Treatment, and a Window of Opportunity Trial With Cisplatin in Patients With Head and Neck Cancer