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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Hypopharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma or Larynx Cancer
and you are
between 18 and 70
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This trial is to determine what dose of a drug called AZD1775 can safely be given in combination with cisplatin before surgery and with chemo-radiotherapy after surgery in patients with Head and Neck Cancer. The Investigators will also get some preliminary information regarding the effectiveness of this combined treatment.

Provided treatments

  • Drug: AZD1775
  • Drug: Cisplatin
  • Radiation: Radiotherapy

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03028766. The sponsor of the trial is University of Birmingham and it is looking for 9 volunteers for the current phase.
Official trial title:
A Phase I Trial of WEE1 Inhibition With Chemotherapy and Radiotherapy as Adjuvant Treatment, and a Window of Opportunity Trial With Cisplatin in Patients With Head and Neck Cancer