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Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running (NCT03028454)

The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function following downhill running. Long-distance running is often associated with acute muscle pain, swelling, and reduced muscle functioning, and consequently, many runners utilize non-steroidal anti-inflammatory drugs (NSAID). NSAID use is associated with gastrointestinal side-effects such as stomach discomfort, nausea, dyspepsia, asymptomatic ulcers, and symptomatic ulcers that, although rare, can be fatal. Ginger is a botanical compound that is Generally Recognized as Safe by the Food and Drug Administration (FDA). Evidence from osteoarthritis, dysmenorrhea, and resistance-training models indicate that ginger is effective at reducing general pain and muscle soreness. Therefore, this study will supplement 60 runners with roughly 1.5 g/day of ginger root or a placebo for 2 days prior to, the day of, and 2 days after downhill running. Participants will be evaluated for muscle soreness and function before and after the downhill run.
  • : Ginger Root
    Capsules containing 250 mg of ginger root extract standardized to contain at least 5% gingerol compounds, as well as an additional 225 mg of regular ginger root.
    • : Placebo
      Capsules containing rice flour powder.
      Ages eligible for Study
      18 Years to 65 Years
      Genders eligible for Study
      Accepts Healthy Volunteers
      Accepts Healthy Volunteers
      Inclusion Criteria:
      • Be currently running ≥10 miles per week
      • Have completed at least one run >40 minutes over the past month
      Exclusion Criteria:
      • Have no allergies to ginger
      • Willing to avoid pain-relieving medications for the duration of the study
      • Have no history of bleeding disorders nor currently taking blood thinners

      1 locations

      United States (1)
      • Human Performance Laboratory
        Not specified
        Norfolk, Virginia, United States, 23529
      31 December, 2016
      17 December, 2017
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