The purpose of this study is to determine if the injection of Platelet-rich plasma (PRP) is
effective in reducing alveolar bone loss that happens after each rapid maxillary expansion
(RME) on the buccal aspect of the posterior teeth.
16 patients with a skeletal maxillary constriction aged between 10-16 years old will get into
orthodontic treatment to widen the maxilla using Hyrax appliance.
An amount of patient blood will be withdrawn and centrifuged to get PRP. Then the PRP will be
injected in one half of each patient mouth in a split-mouth design, beneath the buccal
periosteal of the first molars and first premolars, the halves will be chosen randomly.
High resolution CBCT images will be taken before and after orthodontic treatment to analyze
buccal bone thickness and height changes.