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More info
You can access this
clinical trial
if you have
Raynaud Phenomenon Due to Trauma, Raynaud Disease, System; Sclerosis, Lupus Erythematosus, Systemic, Dermatomyositis or Ultrasound Therapy; Complications
and you are
between 13 and 99
years old
This is an early phase trial to investigate
how or whether the drug affects your body.
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The purpose

Objective: To compare the efficacy of topical 10% nifedipine versus 5% sildenafil in patients with secondary Raynaud's phenomenon (RP). Methods: A randomized, double-blind, placebo-controlled pilot study took place in 10 patients with secondary RP. Topical 10% nifedipine on one hand and 5% sildenafil on the other hand were applied. The thumbs didn't receive any cream and served as a control group. The primary outcome was the improvement of blood flow and vessel diameter of the digital arteries measured by high frequency color Doppler ultrasound before and 1 hour after treatment.

Provided treatments

  • Drug: 10% nifedipine cream
  • Drug: 5% sildenafil cream

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03027674. The sponsor of the trial is Pontificia Universidad Catolica de Chile and it is looking for 10 volunteers for the current phase.
Official trial title:
"Color Doppler Ultrasound Comparison of Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud: A Randomized, Double-blind, Placebo-controlled Pilot Study"