Objective: To investigate the effects of levonorgestrel-releasing intrauterine system
(LNG-IUS) for symptomatic adenomyosis.
Methods: From December, 2006 to December, 2014, symptomatic patients of adenomyosis diagnosed
(with dysmenorrhea and/or menorrhea) by transvaginal ultrasound in outpatient or inpatient
clinics of Peking Union Medical College Hospital were given the treatment of LNG-IUS. Before
and after placement of LNG-IUS, during each following period, all the parameters were
recorded prospectively, including carrying status of IUS, symptoms and scores of
dysmenorrhea, menstruation scores, biochemical indicators, physical parameters, menstruation
patterns and adverse effects.
Primary outcome measures: symptoms and scores of dysmenorrhea and menorrhea
Second outcome measures: carrying status of IUS