Cytological diagnosis of hepatic angiosarcoma by fine-needle aspiration (FNA) or imprint
cytology is difficult due not only to its various cytomorphologic features but also clinical
rarity. Vasoformative features, such as pseudo-acini, branching pseudo-capillary structure,
and intracytoplasmic lumina, are clues to achieve the diagnosis. But these features are not
always present. In order to find clues for cytological diagnosis of angiosarcoma, we
collected cases of hepatic angiosarcoma to study their cytological features. And then
compared these features with those in their histopathological biopsy or resection.