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Adherence to Venous Thromboembolism Prophylaxis Guidelines in Hospitalized Elders (NCT03025100)

National Institutes of Health (NIH)
National Institute on Aging (NIA)
Guideline directed use of pharmacologic Venous thromboembolism (VTE) prophylaxis emphasizes mobility evaluation. Mobility is a key component of risk stratification. Poor mobility evaluation by providers may be a significant barrier to appropriate use of VTE prophylaxis. The investigators aim is to propose to determine whether level of mobility during hospitalization is being used to influence use and duration of VTE prophylaxis among medically ill hospitalized elders. To achieve this aim, the investigator will collect prospective observational data to objectively measure inpatient mobility using patient mounted accelerometers during patient hospital stays. The investigator's goal is to improve the appropriateness of use of VTE prophylaxis among those in which the risks of harm may outweigh the benefit. Results from this study will provide important insights about use of risk assessment, and the relationship between patient mobility and VTE prophylaxis. These results are critical to understanding how to take the next steps toward improving the appropriate use and safety of anticoagulants in hospitalized older adults. Information from this study could be used in future proposals to study interventions to ultimately improve hospital practice in the care of older adults.
Ages eligible for Study
60 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Inclusion Criteria:
  • Age of 60 or older
  • Admitted to General Medicine at Duke University
Exclusion Criteria:
  • Clear contraindications to pharmacologic VTE prophylaxis
  • Receiving surgery during their index hospital stay
  • On observation admission status
  • On negative pressure room respiratory isolation
  • Wrist site is not available, i.e. wearing bilateral wrist IVs, skin breakdown at the time of screening
  • Ankle site is not available, i.e. patients with leg ulcer at the time of screening
  • Lacking decision-making ability (such as from severe cognitive impairment) and no LAR available
  • Non-English speakers

1 locations

United States (1)
  • Duke University Medical Center
    Not specified
    Durham, North Carolina, United States, 27701
31 January, 2016
29 March, 2017
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