Retinoschisis / Macular Detachment / High Myopia
Sun Yat-sen University
Macular schisis associated with macular detachment is a one of the complications of high myopia. There is controversy in the primary treatment for this situation. This study will compare the effects of macular buckling + gas injection versus vitrectomy + internal limiting membrane peeling + gas tamponade in a cohort of highly myopic eyes with macular retinal detachment associated with macular hole.
- Procedure: Macular bucklingSurgical procedures of macular buckling, drainage of aqueous fluid (0.1-0.2 ml) through limbal paracentesis, and inject gas ( C3F8 100%, 0.2ml-0.3ml) into vitreous body through pars plana, under systemic anesthesia.
- Procedure: VitrectomySurgical procedures of small gauge vitrectomy, internal limiting membrane peeling, and gas (C3F8, 14%) tamponage, under local or systemic anesthesia
|Ages eligible for Study||18 Years to 70 Years|
|Genders eligible for Study||All|
|Accepts Healthy Volunteers||No|
- axial length ≥ 26.5 mm or refractive error (spherical equivalent) ≥ 8.0 diopter
- macular schisis
- macular retinal detachment
- evidence of posterior staphyloma on clinical examination
- severe macular scar
- macular detachment which extended to the peripheral retina (i.e., extension beyond the major vascular arcades in more than one quadrant)
- prominent vitreomacular traction
- a history of vitrectomy or macular buckle
- intraocular active hemorrhage or inflammation
- any media opacity which precluded imaging or clinical evaluation of the macula
A randomized, open label, single center study comparing the efficacy of macular muckle + gas injection versus internal limiting membrane peeling + gas tamponade on macular schisis associated with macular detachment in eyes with high myopia.
- Zhongshan Ophthalmic CenterNot specifiedGuangzhou, Guangdong, China, 510060
active not recruiting
31 March, 2015
14 August, 2017