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You can access this
clinical trial
if you have
Consciousness Disorder
and you are
between 18 and 85
years old
-
The phase for this study is not defined.
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The purpose

Severe brain injuries lead to disorders of consciousness after coma. During this awakening period, detection of arousal is critical to the adaptation of medical strategy, but global paralysis, including facial expression, make the clinical assessment very difficult. Emotional facial expressions are a significant part of this clinical assessment. They are both a landmark of the internal state of the patient (comfort versus discomfort) and a landmark of the relational level with his environment. Visible emotional facial expression is a large temporal phenomenon lasting a couple of seconds, while a microexpression is barely noticeable and very brief. These micro expressions are usually produced when one tried to voluntary hide emotional expressions. In this study, we hypothesize that some patients awakening from coma could still produce microexpression before being able to produce visible emotional facial expressions. This ability to produce micro-expression could be an early landmark of relational awakening in severe brain lesions.

Provided treatments

  • Other: Detection of arousal
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Tris trial is registered with FDA with number: NCT03023657. The sponsor of the trial is Centre Hospitalier Universitaire de Saint Etienne and it is looking for 30 volunteers for the current phase.
Official trial title:
Detection of Arousal With Facial Micro-expression in Severe Brain-damaged Patient