Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Consciousness Disorder
and you are
between 18 and 85
years old
The phase for this study is not defined.
Show me locations

The purpose

Severe brain injuries lead to disorders of consciousness after coma. During this awakening period, detection of arousal is critical to the adaptation of medical strategy, but global paralysis, including facial expression, make the clinical assessment very difficult. Emotional facial expressions are a significant part of this clinical assessment. They are both a landmark of the internal state of the patient (comfort versus discomfort) and a landmark of the relational level with his environment. Visible emotional facial expression is a large temporal phenomenon lasting a couple of seconds, while a microexpression is barely noticeable and very brief. These micro expressions are usually produced when one tried to voluntary hide emotional expressions. In this study, we hypothesize that some patients awakening from coma could still produce microexpression before being able to produce visible emotional facial expressions. This ability to produce micro-expression could be an early landmark of relational awakening in severe brain lesions.

Provided treatments

  • Other: Detection of arousal
Wondering what is the locations section for?
We will connect you to the doctor responsible for this trial and help you get more information.

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03023657. The sponsor of the trial is Centre Hospitalier Universitaire de Saint Etienne and it is looking for 30 volunteers for the current phase.
Official trial title:
Detection of Arousal With Facial Micro-expression in Severe Brain-damaged Patient