The prospective observational study entitled "Heidelberg Study on Diabetes and Complications"
is designed to Monitor the presence and development of diabetic complications in type 1 and
type 2 diabetic patients, as well as pre-diabetics. Mail Goal is to detect new metabolic
mechanisms or new risk factors for the development of diabetic complications in order to
identify risk-subgroups. Non-diabetic controls will be enrolled for reference and comparison.