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Your journey
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More info
You can access this
clinical trial
if you have
Ammonia Metabolism
and you are
This is an advanced phase trial assessing
the effectiveness of the new treatment before being released on the market.
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The purpose

L-carnitine is synthesized from lysine and methionine. Postmortem concentrations of carnitine in liver, muscle, heart, kidney, and brain averaged only one-fourth to one-third those in corresponding tissues of eight normally nourished non-hepatic patients who died after an acute illness of a 1-3-day duration. In the recent years, it has been reported that sirtuin 3 (SIRT3) is protective against acute kidney injury (AKI) and suggest that enhancing SIRT3 to improve mitochondrial dynamics has potential as a strategy for improving outcomes of renal injury. In the current study, it is the first clinical interventional research whether L-carnitine corrects ammonia metabolism associated with liver injury in hepatectomized patients.

Provided treatments

  • Drug: L-carnitine
  • Other: usual intake

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03021876. The sponsor of the trial is Kochi University and it is looking for 80 volunteers for the current phase.
Official trial title:
L-carnitine Corrects Ammonia Metabolism in Hepatectomized Patients