Comparison Efficacy of 14-day Concomitant therapy between levofloxacin and Clarithromycin on
the Eradication of Helicobacter Pylori in Syrian population
Drug: Clarithromycin 500Mg Oral Tablet
Drug: Levofloxacin 500Mg Oral Tablet
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Full eligibility criteria for NCT03021590
Ages eligible for Study
18 Years to 75 Years
Genders eligible for Study
Accepts Healthy Volunteers
Patients are aged greater than 18 years old who have H. pylori infection diagnosed by any of following three methods: I-Positive rapid urease test (CLOtest). II-Histologic evidence of H. pylori by modified Giemsa staining. III-Positive 13C-urea breath test. without prior eradication therapy and are willing to receive therapy.
Children and teenagers aged less than 18 years.
Previous eradication treatment for H. pylori.
Patients who took any drug, which could influence the study results such as proton pump inhibitor, H2 blocker, mucosal protective agent and antibiotics.
History of gastrectomy.
Gastric malignancy, including adenocarcinoma and lymphoma,
Previous allergic reaction to antibiotics (Amoxicillin, Tinidazole , Levofloxacin) and prompt pump inhibitors (Es-omeprazole).
Contraindication to treatment drugs.
Pregnant or lactating women.
Severe concurrent disease. Liver cirrhosis. Chronic kidney disease.
Patients who cannot give informed consent by himself or herself.
All locations for NCT03021590
Syrian Arab Republic (1)
Damascus, Syrian Arab Republic, +963
View full eligibility
Tris trial is registered with FDA with number: NCT03021590. The sponsor of the trial is Damascus Hospital and it is looking for 0 volunteers for the current phase.
Official trial title: Comparison Efficacy of 14-day Concomitant Therapy:Clarithromycin vs.Levofloxacin in Eradication of H.Pylori
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