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More info
You can access this
clinical trial
if you have
Hemodynamic Instability, Cardiac Output, High or Peroperative Complication
and you are
over 18
years old
-
The phase for this study is not defined.
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The purpose

To evaluate the impact of perioperative, algorithm driven, hemodynamic therapy based on individualized fluid and cardiac output optimization on postoperative moderate and severe complications in patients undergoing major abdominal surgery including visceral, urological, and gynecological operations. In the proposed study, hemodynamic therapy is tailored individually to each patient, based on individual preload optimization by the functional parameter "pulse pressure variation (PPV)" and based on an individually titrated goal of cardiac index. The proposed study therefore further develops the concept of hemodynamic goal-directed therapy to individually set goals and is designed to assess its impact on morbidity and mortality.

Provided treatments

  • Procedure: Individualized Goal Directed Therapy
  • Procedure: Control Group
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Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03021525. The sponsor of the trial is Universitätsklinikum Hamburg-Eppendorf and it is looking for 380 volunteers for the current phase.
Official trial title:
Individualized Perioperative Hemodynamic Goal-directed Therapy in Major Abdominal Surgery (iPEGASUS-trial) - A Multi-center, Prospective, Randomized Trial