Your journey
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More info
You can access this
clinical trial
if you have
Endstage Renal Disease
and you are
over 18
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require dialysis. It works by blocking a hormone (aldosterone) in your body that causes high blood pressure and can damage the heart. Although spironolactone is very effective in patients that do not require dialysis, we do not know if spironolactone is effective in dialysis patients. Our research will help determine if spironolactone reduces heart failure and heart related deaths in dialysis patients. The purpose of this study is to determine if spironolactone reduces death or hospitalization for heart failure and is well tolerated in patients that require dialysis.

Provided treatments

  • Drug: Spironolactone 25Mg Tablet
  • Drug: Placebo Oral Tablet
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Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03020303. The sponsor of the trial is Population Health Research Institute and it is looking for 2750 volunteers for the current phase.
Official trial title:
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease