Background: Radical hysterectomy is an important therapy for early cervical cancer.
Disfunction of urinary dynamics is the most common postoperative adverse effects, which had
negative impact on patients' quality of life. Nerve sparing radical hysterectomy (NSRH) could
reserve inferior hypogastric plexus (IHP) innervating bladder, hence improving postoperative
urinary dynamics. Furthermore impact of different energy instruments on urinary dynamic isn't
Objectives: This study is to compare urinary dynamics before and after NSRH, and to analyze
the difference between BiClamp forcep (BiClamp® forcep, ERBE Elektromedizin, GmbH, Tuebingen,
Germany) and water jet (ERBEJET®2) about the effects of dissecting IHP.
Study population: Cervical cancer of FIGO IB stage, among which 120 cases are enrolled to
randomly allocated to BiClamp group or water jet group.
Intervention: Patients accept NSRH which all will be accomplished by Professor Ming Wu.
Methods: All surgical patients are accessed via urinary dynamics before and four months after
NSRH. On the 14th day after surgeries, urinary catheter will be removed and residual urine
volume (RUV) will be measured. For patients of RUV > 100 ml, urinary catheter will be
Primary study endpoint: the successful rate of removing urinary catheter on the 14th day
Secondary study endpoint: urinary dynamics four months after NSRH.