Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Castration-Resistant Prostatic Cancer, Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer or Hormone-Refractory Prostate Cancer
and you are
over 18
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
Show me locations

The purpose

This clinical trial studies cognitive function in men with prostate cancer treated with androgen receptor directed therapies such as abiraterone acetate and enzalutamide. The investigators use MRI imaging (non-invasive, non-contrast) to see whether there are changes in brain structure or activity related to treatment that may be related to changes in cognitive function. The investigators are also looking for genetic variations that might make patients more or less sensitive to cognitive changes during treatment for prostate cancer.

Provided treatments

  • Biological: GnRH agonist/antagonist
  • Drug: Prednisone
  • Drug: Abiraterone Acetate
  • Drug: Enzalutamide
Wondering what is the locations section for?
We will connect you to the doctor responsible for this trial and help you get more information.

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03016741. The sponsor of the trial is Northwestern University and it is looking for 100 volunteers for the current phase.
Official trial title:
Cognitive Effects of Androgen Receptor (AR) Directed Therapies for Advanced Prostate Cancer