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Your journey
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More info
You can access this
clinical trial
if you have
Partial or Total Hip Arthroplasty or Ex-vivo Preparat of Femoral Head
and you are
between 18 and 120
years old
This is an observational trial.
You are contributing to medical knowledge about your condition.
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The purpose

The subchondral bone, formed by the subchondral bone plate and the subarticular spongiosa, plays a key role in supporting the articular cartilage. Marrow stimulation techniques such as subchondral drilling are clinically important treatment options for symptomatic small cartilage defects. However, The heat generated from the metal-bone interface during drilling due to the friction can cause thermal osteonecrosis. , recent clinical evidence suggests that they may induce alterations in the subchondral bone plate such as intralesional osteophytes, which persist and may play a role in the degeneration of the repair tissue. Little is known about whether they induce deleterious changes in the Human Chondral & Subchondral bone. The aim of this study was to compare the condral & Sub-chondral Histoligical damage induced by different drilling techniques. To the best of our knowledge this is the first time to inspect it, In- Situ, on Human tissue.

Provided treatments

  • Procedure: microfracture techniques

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03016299. The sponsor of the trial is Meir Medical Center and it is looking for 40 volunteers for the current phase.
Official trial title:
The Histological Effect of Various Microfracture Techniques on Human Chondral & Sub-chondral Tissue - an Ex-Vivo Study