The aim of this study is to determine whether common CYP1A2 gene polymorphisms effect
metabolism of theophylline in Han and Uygur Patients with chronic obstructive pulmonary
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Full eligibility criteria for NCT03015090
Ages eligible for Study
18 Years to 75 Years
Genders eligible for Study
Accepts Healthy Volunteers
Aged 18-75 years,Weight 40-80kg COPD patients, male or female; regularly visiting our hospital; taking a sustained-release preparation of theophylline continuously for at least 2 weeks
Patients with renal or hepatic dysfunction; Patients with congestive heart failure; Patients with hypothyroidism or hyperthyroidism; Patients currently taking drugs likely to effect theophylline metabolism or who had taken such drugs in the preceding week; Patients with extreme obesity Patients with very severe Chronic Obstructive Pulmonary Disease(COPD)
All locations for NCT03015090
Kashgar 1st People's Hospital
Kashgar, Xinjiang, China, 844000
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Tris trial is registered with FDA with number: NCT03015090. The sponsor of the trial is XiaoGuang Zou and it is looking for 100 volunteers for the current phase.
Official trial title: Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline in Han and Uygur Patients With COPD
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