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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Insulin Resistance or Endothelial Dysfunction
and you are
between 18 and 50
years old
This is a medium phase trial determining
the safety and dosage of the new treatment, as well as its efficacy.
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The purpose

This proposal will test the hypothesis that chronic treatment with sildenafil with and without the use of nitric oxide substrate, L-arginine, protects against fatty acid induced impairment of endothelial function, improves insulin-stimulated microvascular recruitment, insulin sensitivity and glucose uptake in CD36 rs3211938 G-allele carriers.

Provided treatments

  • Drug: Sildenafil Citrate

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT03012386. The sponsor of the trial is Vanderbilt University Medical Center and it is looking for 83 volunteers for the current phase.
Official trial title:
Role of CD36 in Nutrient Delivery and Its Dysfunction in African Americans