The aim of this study is to investigate the short and long term efficacy and the safety of
SCRT treatment for PAR
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Full eligibility criteria for NCT03009136
Ages eligible for Study
18 Years to 60 Years
Genders eligible for Study
Accepts Healthy Volunteers
age 18-60 years
presence of two or more nasal symptoms (rhinorrhea, nasal congestion, nasal itching and sneezing) with severity score ≥ 2 (0 = no symptom, 1 = mild symptom, 2 = moderate symptom, and 3=severe symptom)
presence of nasal symptoms more than 2 consecutive years; and
positive reaction to the one or more perennial allergen in skin prick test.
treatment with nasal/oral corticosteroids within the past month; nasal cromolyn or tricyclic antidepressants within the past two weeks; or nasal/oral decongestants, nasal/oral antihistamines, or antileukotrienes within the past week
presence of rhinosinusitis (paranasal sinus X-ray demonstrating mucosal thickening, or partial or complete opacification of the paranasal sinuses)
presence of hypertension (systolic ≥ 180 mmHg or diastolic ≥ 100 mmHg)
presence of abnormal liver function (aspartate transaminase (AST) or alanine transaminase (ALT) ≥ 100 IU/L) or abnormal renal function (blood urea nitrogen (BUN) ≥ 30 mg/dL or creatinine ≥ 1.8 mg/dL (male), 1.5 mg/dL (female))
presence of neoplasm, severe systemic inflammation, other systemic disease that affects rhinitis
history of drug allergy
history of anaphylaxis for allergic tests
pregnancy or lactation
participation of other clinical study within the past 3 months.
All locations for NCT03009136
Korea, Republic of (1)
Kyung Hee University Hospital at Gangdong
Seoul, Korea, Republic of, 05278
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Tris trial is registered with FDA with number: NCT03009136. The sponsor of the trial is Kyung Hee University Hospital at Gangdong and it is looking for 154 volunteers for the current phase.
Official trial title: Efficacy and Safety of So-Cheong-Ryong-Tang on Perennial Allergic Rhinitis: Study Protocol for a Double-blind, Randomized, Parallel-group, Multi-center Trial
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