To define the long-term incidence and frequency of ISR follow DES implantation. Compare the
clinical presentation, treatment and intervention success among de novo coronary artery
stenosis and DES ISR.
Compare short- and long-term outcomes of de novo coronary artery stenosis and DES ISR,
assessed by incidence of mortality, MACE, MI, and TLR/TVR at index hospitalization, 30 days,
6 months, 1 year, 3 years, and 5 years, if available.