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Your journey
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More info
You can access this
clinical trial
if you have
Ischemic Stroke
and you are
between 18 and 101
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This is a phase 1, blinded-outcome, randomized, placebo controlled study to investigate the safety and feasibility of super-selective intra-arterial administration of verapamil and magnesium sulfate immediately following successful endovascular thrombectomy as a potential neuroprotective synergistic therapeutic strategy in emergent large vessel occlusion stroke. This trial represents the first time that magnesium sulfate will be evaluated in human subjects as a superselectively administered neuroprotective agent administered in an acute time frame as an adjunct to intra-arterial thrombectomy. Furthermore, it will represent the first trial to evaluate combinational therapy for acute stroke neuroprotection.

Provided treatments

  • Drug: Verapamil and Magnesium Sulfate
  • Other: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02912663. The sponsor of the trial is Justin Fraser and it is looking for 10 volunteers for the current phase.
Official trial title:
Magnesium And Verapamil After Recanalization in Ischemia of the Cerebrum (MAVARIC) in the Kentucky Regional Population: a Clinical and Translational Study.