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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Ischemic Stroke
and you are
between 18 and 101
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This is a phase 1, blinded-outcome, randomized, placebo controlled study to investigate the safety and feasibility of super-selective intra-arterial administration of verapamil and magnesium sulfate immediately following successful endovascular thrombectomy as a potential neuroprotective synergistic therapeutic strategy in emergent large vessel occlusion stroke. This trial represents the first time that magnesium sulfate will be evaluated in human subjects as a superselectively administered neuroprotective agent administered in an acute time frame as an adjunct to intra-arterial thrombectomy. Furthermore, it will represent the first trial to evaluate combinational therapy for acute stroke neuroprotection.

Provided treatments

  • Drug: Verapamil and Magnesium Sulfate
  • Other: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02912663. The sponsor of the trial is Justin Fraser and it is looking for 10 volunteers for the current phase.
Official trial title:
Magnesium And Verapamil After Recanalization in Ischemia of the Cerebrum (MAVARIC) in the Kentucky Regional Population: a Clinical and Translational Study.