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More info
You can access this
clinical trial
if you have
Pre-Eclampsia, HELLP Syndrome or Eclampsia
and you are
over 18
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

NSAIDs, specifically cyclo-oxygenase (COX) inhibitors, are known to increase blood pressure over time in non-pregnant adults, but the effect of COX-inhibitors on blood pressure in the setting of preeclampsia have not been well studied. This study aims to assess the effect of avoiding COX-inhibitors on postpartum blood pressure control among women diagnosed with preeclampsia with severe features. Eligible women will be randomized to receive either acetaminophen or ibuprofen for postpartum pain control. Both agents are first line therapies for pain control although ibuprofen has better pain control than acetaminophen. The primary outcome will be duration of postpartum severe-range hypertension.

Provided treatments

  • Drug: Acetaminophen
  • Drug: Ibuprofen

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02911701. The sponsor of the trial is University of New Mexico and it is looking for 100 volunteers for the current phase.
Official trial title:
Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features