Elderly (i.e.>75 yrs) represent about 40% of incident dialysis patients in the French REIN
Registry and are growing population in high income countries. Those elderly patients with CKD
have a high risk of dying within the first months of dialysis start or could have a good
long-term prognosis suggesting kidney transplantation access. Elderly patients with CKD also
have a higher risk of dying than reaching ESRD. Therefore, outcomes of elderly patients with
advanced CKD need to be better described and understood to be able to give accurate
information to the patients and their relatives and help decision making concerning the
treatment strategy including several options (i.e preemptive kidney transplantation, in
center or home dialysis and conservative care). In France we have information about patients
who started dialysis with French dialysis registry (REIN) but not about elderly patient
treated with conservative care. Then we don't have information about description of the
therapeutic project in this population and their evolution in a prospective cohort design.
Finally we need to identify patients with high risk of early mortality to help shared
decision making for better care organisation.
The project of the study is the development of a French multicenter prospective cohort
including elderly patients more than 75 years old reaching ESRD. Objectives are as follow:
Description of the characteristics of the population such as, clinical and social conditions,
medicine treatment, therapeutic project declared by nephrologist and laboratory value at
Description of the evolution of therapeuic project, kidney function and the outcomes defined
as death or dialysis or kidney transplantation.
Development of a mortality prognosis tools to help decision making in this population.