RCT to investigate whether metformin co-treatment would improve IVF outcomes in overweight
and obese women with PCOS.
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Full eligibility criteria for NCT02910817
Ages eligible for Study
20 Years to 40 Years
Genders eligible for Study
Accepts Healthy Volunteers
The inclusion criteria restricted the patients to 39 years old with basal FSH < 10 IU/ml and normal TSH and prolacin.
Exclusion criteria were diabetes mellitus (excluded by GTT), renal or liver disease, associated male factor, documented tubal factor or pelvic adhesions, elevated 17 alfa hydroxyprogesterone level and FSH ≥10 IU/ml. We also excluded the women who started program or medications to reduce their weight and those who their partner has abnormal semen parameters according to the world health organization parameters (WHO, 2010)
All locations for NCT02910817
Assiut, Egypt, 71515
View full eligibility
Tris trial is registered with FDA with number: NCT02910817. The sponsor of the trial is Assiut University and it is looking for 102 volunteers for the current phase.
Official trial title: Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese Polycystic Ovary Syndrome Women; A Quasi Experimental Study
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