This is an open-label positron emission tomography/near infrared (PET/NIRF) study to
investigate the imaging navigation performance and evaluation efficacy of dual modality
imaging probe 68Ga-BBN-IRDye800CW in glioblastoma (GBM) patients. A single dose of
40μg/111-148 Mega-Becquerel (MBq) and 1.0 mg/ml 68Ga-BBN-IRDye800CW will be injected
intravenously before the operation and intraoperative respectively. Visual and
semiquantitative method will be used to assess the PET images and real-time margins
localization for surgical navigation.