This study seeks to evaluate the effect of intepirdine (RVT-101) on gait and balance in
patients with Alzheimer's Disease, Dementia with Lewy Bodies or Parkinson's Disease Dementia.
Drug: RVT-101 35 mg
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Locations near you
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Full eligibility criteria for NCT02910102
Ages eligible for Study
50 Years to 89 Years
Genders eligible for Study
Accepts Healthy Volunteers
Male or female subject with a clinical diagnosis of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), or Parkinson's disease dementia (PDD).
Mini Mental State Examination score 14 to 26
Gait impairment, as assessed by history gathered by the clinical investigator and quantitative measurements
Subjects must be on stable background acetylcholinesterase inhibitor therapy Key
History and/or evidence of any other CNS disorder that could be interpreted as a cause of dementia (in the opinion of the investigator)
Any clinically relevant concomitant disease which, in the opinion of the investigator, makes the subject unsuitable for inclusion in the study.
All locations for NCT02910102
United States (11)
Phoenix, Arizona, United States, 85013
Simi Valley, California, United States, 93065
Temecula, California, United States, 92591
Boca Raton, Florida, United States, 33431
Hallandale Beach, Florida, United States, 33009
Miami, Florida, United States, 33137
Pensacola, Florida, United States, 32502
Columbus, Georgia, United States, 31909
Indianapolis, Indiana, United States, 46202
Ann Arbor, Michigan, United States, 48106
Columbus, Ohio, United States, 43210
View full eligibility
Tris trial is registered with FDA with number: NCT02910102. The sponsor of the trial is Axovant Sciences Ltd. and it is looking for 38 volunteers for the current phase.
Official trial title: A Phase 2, Double-blind, Randomized, Placebo-controlled Crossover Study Evaluating the Effect of RVT-101 on Gait and Balance in Subjects With Alzheimer's Disease, Dementia With Lewy Bodies, or Parkinson's Disease Dementia
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