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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Malaria, Pregnancy Malaria, Cardiotoxicity, Cardiac Safety or Parasitemia
and you are
between 18 and 34
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

Sulfadoxine-pyrimethamine (SP) is currently recommended by the World Health Organization for use as intermittent preventive treatment against malaria in pregnancy (IPTp) in areas of moderate to high malaria transmission. However, in some locales malaria parasites have lost sensitivity to SP, compromising its protective effect. Dihydroartemisinin-piperaquine (DP) is a candidate replacement for SP. This trial is designed to confirm the cardio-safety of DP compared to SP amongst pregnant women in Tanzania.

Provided treatments

  • Drug: sulfadoxine-pyrimethamine (SP)
  • Drug: dihydroartemisinin-piperaquine (DHA-PQP)

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02909712. The sponsor of the trial is London School of Hygiene and Tropical Medicine and it is looking for 201 volunteers for the current phase.
Official trial title:
Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania