Some Primary Immune Deficiencies can be associated with an inflammatory bowel disease,
mimicking Crohn disease : the Chronic Granulomatous Disease (CGD), the XIAP deficiency, and
the TTC7A deficiency.
This inflammatory bowel disease is frequent but inconstant, raising questions about other
factors contributing to the disease. The aim of our study is to analyze, describe and compare
the gut microbiota of patients with those primary immune deficiency, with or without
The investigators can expect, in the long term, to compare on a same patient, the gut
microbiota evolution, and to assess the role of gut microbiota modifications on the onset of
an inflammatory bowel disease.