Aim. To investigate the effect of an intradialytic aerobic and resistance cycling exercise
program (IARCEP) on depression, fatigue, and quality of life (QOL) in end-stage renal disease
(ESRD) patients receiving haemodialysis, and further determine the effect of mediation
through self-efficacy and resilience in patients receiving the IARCEP.
Background. Depression and fatigue are common in ESRD patients undergoing haemodialysis,
which negatively affects their QOL. Exercise can mitigate this effect. Patient's
self-efficacy and resilience may be crucial mediators in exercise.
Design. This study was a randomised controlled trial. Method. Seventy-six participants were
randomly assigned to either a control or exercise group. Both groups received routine care;
whereas the exercise group participated the 3- months IARCEP. Data were collected at
baseline, the first, second, and third months, over a 14 months in 2013-2014.