This study is designed for patients with a cancer of the oropharynx (tonsils or base of
tongue) caused by the HPV virus. Traditional treatment involves surgery followed by six weeks
of daily radiation therapy. This study investigates a less intense radiation treatment
following surgery that uses half the dose of radiation given over two weeks rather than six
weeks. Patients will be randomly assigned to receive the less intense treatment versus the
traditional treatment by coin flip. Patients are twice as likely to receive the less intense
treatment during randomization.