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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Out-of-hospital Cardiac Arrest
and you are
over 18
years old
The phase for this study is not defined.
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The purpose

ILCOR guidelines recommend Target Temperature Management (TTM) to between 32°C and 36°C after out-of-hospital cardiac arrest, based on low quality evidence. In a previous trial, TTM at 33°C did not confer a survival benefit or improved neurological function, compared to TTM at 36°C. A lower target temperature might be beneficial compared with normothermia and early treatment of fever. Therefore the primary purpose of the TTM2-trial will be to study any differences in mortality, neurological function and quality of life between a target temperature of 33°C and standard care avoiding fever.

Provided treatments

  • Procedure: Targeted temperature management to 33°C
  • Procedure: Standard care with early treatment of fever

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02908308. The sponsor of the trial is Helsingborgs Hospital and it is looking for 1900 volunteers for the current phase.
Official trial title:
Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest (TTM2) - A Randomised Clinical Trial