Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Brain Tumor Recurrent
and you are
between 1 and 80
years old
This is an early phase trial to investigate
how or whether the drug affects your body.
Show me locations

The purpose

The goal of this clinical research study is to establish the safety of simultaneous infusions of methotrexate and etoposide into the fourth ventricle of the brain or resection cavity in patients with recurrent malignant posterior fossa brain tumors. These tumors include medulloblastoma, ependymoma, atypical teratoid/rhabdoid tumor or other malignant brain tumor with recurrence or progression involving anywhere in the brain and/or spine. Patients' disease must have originated in the posterior fossa of the brain.

Provided treatments

  • Drug: Methotrexate
  • Drug: Etoposide
  • Procedure: Ommaya Reservoir
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Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02905110. The sponsor of the trial is The University of Texas Health Science Center, Houston and it is looking for 10 volunteers for the current phase.
Official trial title:
Combination Intraventricular Chemotherapy Pilot Study: Methotrexate and Etoposide Infusions Into the Fourth Ventricle or Resection Cavity in Children With Recurrent Posterior Fossa Brain Tumors