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More info
You can access this
clinical trial
if you have
and you are
between 18 and 70
years old
The phase for this study is not defined.
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The purpose

Serotonergic 5-HT3 receptors in the central nervous system are involved in pain processing after nerve injury. We are interested in learning if 5-HT3 receptor antagonist ondansetron might be an appropriate drug for treating pain after nerve injury (neuropathic pain), by investigating its bio-distribution in the cerebro-spinal fluid, and the genetic variability that may affect that distribution. Study procedures will include iv ondansetron administration, serial blood draws, cerebrospinal fluid (CSF) sampling, pregnancy testing, and possible ECG.

Provided treatments

  • Drug: Ondansetron

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02901054. The sponsor of the trial is Washington University School of Medicine and it is looking for 19 volunteers for the current phase.
Official trial title:
Investigation of Cerebrospinal Fluid (CSF) Pharmacokinetics of Ondansetron