Wound complications after sarcoma resection are frequent and potentially devastating problem.
The burden of surgical wound complications in the lower extremity after preoperative external
beam radiation therapy (EBRT) for soft tissue sarcoma is estimated at 43%. A noninvasive
method of predicting complications would be extremely beneficial. The aim of this study is to
evaluate the relationship between preoperative skin oxygenation and wound outcomes in a
multi-center prospective analysis. This information could lead to a change in practice
regarding surgical timing and adjunctive interventions to improve wound healing outcomes.