The chief aim of this study is to evaluate the difference in tooth sensitivity after having
used a gel containing nano - hydroxyapatite and potassium nitrate
This randomized double-blind clinical study is designed to compare the efficacy in reducing
dentin hypersensitivity of a toothpaste gel containing Nano-hydroxyapatite and potassium
nitrate (Cavex Bite & White ExSense, Cavex Holland BV) with a fluoride-based gel toothpaste (
Colgate, Protection Caries, Palmolive SPA ).
Specific objectives :
To evaluate through standardized tests the dental sensitivity before and after the
application of toothpastes; To compare the variations of dental sensitivity test and control
determination of adverse reactions, such as increased tooth pain and changes in the oral
mucosa after application of the materials.