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More info
You can access this
clinical trial
if you have
Dentin Sensitivity
and you are
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

The chief aim of this study is to evaluate the difference in tooth sensitivity after having used a gel containing nano - hydroxyapatite and potassium nitrate This randomized double-blind clinical study is designed to compare the efficacy in reducing dentin hypersensitivity of a toothpaste gel containing Nano-hydroxyapatite and potassium nitrate (Cavex Bite & White ExSense, Cavex Holland BV) with a fluoride-based gel toothpaste ( Colgate, Protection Caries, Palmolive SPA ). Specific objectives : To evaluate through standardized tests the dental sensitivity before and after the application of toothpastes; To compare the variations of dental sensitivity test and control groups. Safety: determination of adverse reactions, such as increased tooth pain and changes in the oral mucosa after application of the materials.

Provided treatments

  • Other: Cavex Bite&White ExSense
  • Other: Colgate, Protection Caries
  • Other: Placebo gel

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02895321. The sponsor of the trial is Università degli Studi di Sassari and it is looking for 35 volunteers for the current phase.
Official trial title:
Randomized Clinical Trial to Evaluate the Efficacy of Nano-hydroxyapatite Combined With the Potassium Nitrate for the Treatment of Dental Sensitivity