A cerebral pharmacodynamic feedback may help the anesthesiologist to adjust anesthetics
administration. The BIS, which provides a single number resulting from an algorithm
calculated from cortical EEG parameters, may play this role.Moreover, halogenated agents and
propofol may have different EEG effects, which might interfere on measured BIS values.
The aim of this prospective randomized study was to compare, in steady state conditions, the
EEG profiles in children anesthetized with sevoflurane (S) or propofol (P) : for both
anesthetics, the BIS-concentration relationship and raw EEG were analysed at different levels
of general anesthesia.