To determine the accuracy of NIR/US assessment of tumor vasculature and oxygen changes in
predicting and monitoring early neoadjuvant treatment response compared to pathological
Device: Optical Tomography Using Near Infrared Diffused Light Assisted with Ultrasound
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Full eligibility criteria for NCT02891681
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Scheduled to receive neoadjuvant chemotherapy for the treatment of newly diagnosed, locally advanced breast cancer or scheduled to receive neoadjuvant endocrine therapy with the eventual goal of surgery of newly diagnosed clinical stage II-III ER+ HER2- breast cancer (for the endocrine therapy cohort)
At least 18 years of age
Able to understand and willing to sign an IRB-approved written informed consent document
Pregnant and/or breastfeeding
Prior history of breast cancer
Prior history of chest wall radiation
Prior history of breast reconstruction, reduction, or augmentation
All locations for NCT02891681
United States (1)
Washington University School of Medicine
Saint Louis, Missouri, United States, 63110
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Tris trial is registered with FDA with number: NCT02891681. The sponsor of the trial is Washington University School of Medicine and it is looking for 50 volunteers for the current phase.
Official trial title: Ultrasound and Near Infrared Imaging for Predicting and Monitoring Neoadjuvant Treatment
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