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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Major Depression
and you are
between 45 and 75
years old
The phase for this study is not defined.
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The purpose

Project:EVO is a video-game based intervention that targets neural networks associated with cognitive control. The same networks have been implicated in poor treatment response in middle and older aged adults suffering from major depression. Related work has demonstrated that healthy older adults show significant improvement in cognitive control. In a very small sample of older adults suffering from depression (n=12), we found similar improvements in selective attention and working memory after 4 weeks of intervention, along with improvements in mood comparable to participants receiving an evidence-based psychotherapy. The intent of this proposal is to first determine if at least 2/3 of participants who use Project:EVO for four weeks demonstrate significant improvements in the function of these neural networks, and if improvements are observed, to conduct a second study to see if changes in neural network functions are associated with changes in mood. If we show that Project:EVO improves neural function and mood to a greater degree than a placebo cognitive training game, we will be in a position to move onto the next phase of study, which is to demonstrate the intervention's efficacy in a much larger sample of adults with depression.

Provided treatments

  • Behavioral: Band Together
  • Other: Control Mobile 3D video game

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02891564. The sponsor of the trial is University of Washington and it is looking for 79 volunteers for the current phase.
Official trial title:
Computerized Intervention Targeting Cognitive Control Deficits in Depressed Adults