During surgery for pelvic organ prolapse, it is common for the surgeon to inject fluid into
the vaginal tissues to help with tissue dissection. It is common that anesthetic medication
is mixed into this fluid to help with pain control after surgery. Usually the pain medication
injected is short-acting. In this study the investigators plan to compare the usual
short-acting injected pain medication with a long-acting injected pain medication to evaluate
whether this improves pain control after surgery.
One type surgical procedure for prolapse will be evaluated. The procedure is sacrospinous
ligament fixation. This is suspension of the vagina to treat pelvic organ prolapse. Study
participants will be randomized to one of two study groups:
1. Lidocaine group (short-acting medication).
2. Liposomal bupivacaine group (long-acting medication)
Information will be collected on study participants, including: demographics, procedure data,
and post-operative information. The primary outcome of this study is determine if use of
long-acting injected local anesthesia at the time of sacrospinous ligament fixation leads to
less post-operative pain compared to short-acting local anesthesia.
Secondary outcomes include:
1. post-operative opioid medication use
2. return to baseline pain status
3. post-operative time to first bowel movement
4. post-operative antiemetic use (nausea medication)
5. results of voiding trial after surgery
6. patient satisfaction with pain control