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Your journey
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More info
You can access this
clinical trial
if you have
Fibroids, Uterine or Leiomyoma
and you are
between 35 and 50
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This pilot study evaluates the safety and tolerability of a single injection of collagenase enzyme directly into a uterine fibroid in subjects already selected for hysterectomy or myomectomy. Fibroids contain excessive amounts of collagen and it is possible that digestion of collagen may be beneficial in reducing pain and bleeding associated with fibroids. Three subjects will be injected with saline only to evaluate the safety and effectiveness of the injection method. Additional subjects will then be injected with increasing doses of study drug.

Provided treatments

  • Other: Saline
  • Drug: EN3835

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02889848. The sponsor of the trial is Advance Biofactures Corporation and it is looking for 15 volunteers for the current phase.
Official trial title:
An Open Label, Dose Escalation Study to Assess Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) in Subjects With Uterine Leiomyoma (Fibroids)