The investigators performed a randomized, double blind controlled, prospective study method
on observation of Traditional Chinese Medicine (TCM) combined with targeted therapy
maintenance to prolong the efficacy of long-term survival of advanced pulmonary
adenocarcinoma patients. The investigators plan to involve 200 cases for observation in 3
years (100 cases for targeted therapy maintenance, 100 cases for targeted therapy maintenance
plus TCM,), expecting that integrated TCM combined with targeted maintenance therapy has a
better efficacy on prolonging progression-free survival time, overall survival, improving
quality of life(QOL) of patients than that of targeted maintenance therapy.