Dexmedetomidine is a selective α-2 receptor agonist with a sedative and cardiopulmonary
profile that makes it an attractive anesthetic for pediatric patients with congenital heart
disease (CHD). The aim of this study was to investigate the renal protective effect of
dexmedetomidine in the perioperative setting in children with heart disease.
Total 144 pediatric patients allocated dexmedetomidine (DEX) and did not receive the drug
The primary objective of this study was to assess the relationship between the use of
intraoperative dexmedetomidine and the incidence of acute kidney injury in pediatric patients
undergoing cardiopulmonary bypass. The secondary objective was to determine whether there was
an association between dexmedetomidine use and duration of mechanical ventilation or
cardiovascular ICU stay.