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More info
You can access this
clinical trial
if you have
Cervical Ripening or Pregnancy
and you are
over 18
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

According perinatal surveys, induction of labor is performed at more than 20% of pregnant women. According to a survey on the trigger practices in France, prostaglandins are widely used to initiate cervical ripening, usually by laying intravaginal dinoprostone (Propess®). The overall work-up rate due to the use of a single Propess® is 74.6% with 80% of vaginal deliveries. Currently, 25.4% of patients who was not put in work after 24 hours are triggered by oxytocin (Syntocinon®) or directly caesarean. The initial installation of intravaginal dinoprostone limits the use of oxytocin (Syntocinon®) or in lower doses. Using a second Propess® is carried out in several maternity hospitals, as reported by the survey on the cervical ripening practices in France. This second administration could be the solution to reduce the rate of caesarean in France which amounted to 20.8%.

Provided treatments

  • Drug: Dinoprostone
  • Drug: Oxytocine
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Locations near you

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Tris trial is registered with FDA with number: NCT02888041. The sponsor of the trial is University Hospital, Limoges and it is looking for 110 volunteers for the current phase.
Official trial title:
Is There an Interest in Repeating the Vaginal Administration of Dinoprostone (Propess®), to Promote Induction of Labor of Pregnant Women at Term?