Purpose is to show that HHHFNC method is as effective and safe as nCPAPand even more
comfortable than it as non-invasive respiratory support for the prevention of extubation
failure in preterm with gestational age of 26-32 weeks.
Patients requiring mechanical ventilation for at least 6 hours on the first 7 postnatal days
will be included in the study.When patients were Fi O2 < 0,40, Pa CO2 < 65 mmHg, pH> 7.20,
MAP (mean airway pressure) <7 cm H2O, they will be extubated if statistically
stable.Oxygen-air mixture of 4-6 l / min flow rate will be set in HHHFNC group, and pressure
will be set to 5-8 cm H2O in NCPAP group. When flow is 2 l / min, FiO2 is<0.30 at 24 hours
and above, free oxygen will be introduced. In NCPAP group, when pressure is 5 cm H2O and FiO2
< 0.30 at 24 hours and above, free oxygen will be introduced.