Hip and knee osteoarthritis (OA) is an important health problem with a high prevalence and
significant consequences on functional ability, perceived health, restriction of autonomy and
handicap. The weight of multimorbidities and their interaction on functional ability and
perceived health are left unexplored. This project will rely on the cohort KHOALA,
representative, multiregional, of 881 prevalent cases (symptomatic hip and knee OA).
- to describe the evolution over time of pain, functional ability, social participation
and quality of life in subjects with hip and knee OA
- to identify prognosis factors of disease evolution (socio-demographic, clinical, and
other health parameters)
- to determine interactions with comorbidities, other personal and environmental factors
Concurrent objective: to improve measurement of perceived health specific to hip and knee OA
by the OAKHQOL by improving its metrologic performances based on item response theory.
Task 1: To prepare an improved measurement scale, available as a judgment criteria for the
3rd year of cohort follow up, over the april 2010-march 2012 period, the mini-OAKHQOL Task 2:
Evaluation of the cohort in 2010-2012 (year 3 of follow up) in a repeated measure design to
best assess the evolution of perceived health and functional ability over time, and to
identify stability of deterioration of autonomy. Perspectives: This project targets to
provide public health deciders with information of good quality to help them manage
determinants of perceived health in OA subjects, as essential factors to health care resource
utilization in their various modalities.